Melanotan II
Melanotan II is a synthetic cyclic heptapeptide developed as an analogue of α-melanocyte-stimulating hormone (α-MSH). It exhibits activity across multiple melanocortin receptor subtypes and is used in laboratory research exploring melanocortin signalling pathways, pigmentation processes, and receptor interactions. Melanotan II is a non-selective melanocortin receptor agonist in experimental research settings.
Melanotan II
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Melanotan II is a synthetic cyclic heptapeptide developed as an analogue of α-melanocyte-stimulating hormone (α-MSH). It exhibits activity across multiple melanocortin receptor subtypes and is used in laboratory research exploring melanocortin signalling pathways, pigmentation processes, and receptor interactions. Melanotan II is a non-selective melanocortin receptor agonist in experimental research settings.
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Melanotan II is an analogue of α-MSH, designed to improve stability and prolong biological activity relative to the native hormone. It functions as a non-selective melanocortin receptor agonist with activity at multiple receptor subtypes, including:
- MC1R
- MC3R
- MC4R
- MC5R
Its cyclic structure contains a disulphide bridge that enhances structural stability and increases resistance to enzymatic degradation compared with many linear peptide analogues.
Melanotan II is used to investigate melanocortin receptor pharmacology, melanogenesis, pigmentation pathways, and neuroendocrine signalling. Its broad receptor activity profile supports the study of diverse melanocortin-mediated processes, including energy homeostasis and neural signalling.
For research use only.
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