PT-141

PT-141

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PT-141, also known as Bremelanotide, is a synthetic cyclic peptide analogue of alpha-melanocyte-stimulating hormone (α-MSH) studied in experimental models involving melanocortin receptor pharmacology, neuroendocrine signalling, and peptide-mediated cellular processes.

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Derived from the melanocortin peptide family, PT-141 has attracted scientific interest due to its agonist activity at melanocortin receptors, with notable activity at melanocortin-4 receptor (MC4R) and melanocortin-3 receptor (MC3R). Experimental studies have examined its receptor-binding characteristics, melanocortin receptor-mediated intracellular signalling, and molecular mechanisms involved in neuroendocrine communication.

Research applications include:

  • Melanocortin receptor signalling studies
  • MC4R and MC3R pharmacology research
  • Neuroendocrine signalling investigations
  • Peptide-receptor interaction studies
  • Central nervous system signalling research
  • Molecular neurobiology and peptide science investigations
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